Our research work

BigAI is built on research. Our founder, Dr Mahesh Maindarkar, has authored and co-authored more than 200 research papers, with recent work in AI for cardiovascular risk, medical imaging and explainable AI published in leading international journals.

200+ research papers by our founder

17 recent international journal papers listed below and on his faculty profile

2 published patents

MDPI best paper award, Healthcare 2022

Research areas

Cardiovascular and stroke risk stratification
Deep learning models that estimate cardiovascular and stroke risk in patients with conditions such as diabetes, Parkinson’s disease, rheumatoid arthritis, sleep apnoea and COVID-19.
Medical image analysis
Segmentation and classification of intravascular ultrasound, carotid ultrasound and chest X-ray images, including transformer and attention-based architectures.
Explainable and unbiased AI
Methods to make clinical AI transparent, and to detect and reduce bias before models are used on patients.
Radiogenomics and precision medicine
Combining imaging, genomics and polygenic risk scores to personalise risk prediction.
Economics of AI in healthcare
Where AI saves cost in diagnosis and treatment — work recognised with MDPI Healthcare’s 2022 best paper award.
Machine learning and IoT for energy
Energy harvesting and machine-learning control of solar plants, the subject of two published patents.

Selected publications

Recent peer-reviewed journal papers co-authored by Dr Mahesh Maindarkar.

  1. Transformer and attention-based architectures for segmentation of coronary arterial walls in intravascular ultrasound: a narrative review

    Kumari, Katiyar, Bhagawati, Maindarkar et al. (2025). Diagnostics, 15(7), 848.

  2. Segmentation and classification of tuberculosis, pneumonia and COVID-19 in chest images

    Bhongale, Maindarkar, Vyas et al. (2025). Multimedia Tools and Applications.

  3. AI-based cardiovascular and stroke risk assessment in women with autoimmune disorders

    Tiwari, Shrimankar, Maindarkar et al. (2025). Rheumatology International, 45, 14.

  4. Non-invasive cardiovascular risk stratification in obstructive sleep apnoea using AI

    Maindarkar, Khanna, Puvvula et al. (2024). Reviews in Cardiovascular Medicine, 25(12), 463.

  5. Ultrasound radiomics and genomics (UltraAIGenomics) for cardiovascular risk

    Saba, Maindarkar, Johri et al. (2024). Reviews in Cardiovascular Medicine, 25(5), 184.

  6. Polygenic risk scores for cardiovascular disease in an AI framework

    Khanna, Singh, Maindarkar et al. (2023). Journal of Korean Medical Science, 38(46), e395.

  7. Radiogenomics risk predictors in an explainable AI framework for clinical trials

    Saba, Maindarkar, Khanna et al. (2023). Frontiers in Bioscience-Landmark, 28(10), 248.

  8. Economics of artificial intelligence in healthcare: diagnosis vs. treatment (MDPI best paper award 2022)

    Khanna, Maindarkar, Viswanathan et al. (2022). Healthcare, 10(12), 2493.

  9. Deep learning for cardiovascular and stroke risk in diabetic foot infection

    Khanna, Maindarkar, Viswanathan et al. (2022). Journal of Clinical Medicine, 11(22), 6844.

  10. Bias in AI systems for early detection of Parkinson’s disease

    Paul, Maindarkar, Saxena et al. (2022). Diagnostics, 12(1), 166.

Patents

Published Indian patent applications.

  • RF rectenna for energy harvesting at 1.8 GHz to 5.8 GHz to reduce energy crises

    Indian patent application 202021036496, published 4 March 2022

  • Machine learning and Internet of Things approach for solar plant control system and fault detection with energy prediction

    Indian patent application 202021036499, published 4 March 2022

Research collaborations

We work with universities, hospitals and research institutes on joint projects, publications and student research.